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1.
Arq. gastroenterol ; 50(4): 251-256, Oct-Dec/2013. tab, graf
Article in English | LILACS | ID: biblio-950501

ABSTRACT

ContextAge has been considered an independent risk factor for colonoscopy complications, especially when associated with multimorbidity.ObjectivesThe primary objective was to verify the relationships between age, multimorbidity and colonoscopy complications in the elderly.MethodsA retrospective cohort including patients of 60 years or older who had undergone a colonoscopy. Data relating to age, multimorbidities according to the cumulative illness scale for geriatrics and the Charlson index and complications related to bowel preparation and procedure (sedation and exam) were collected.ResultsOf the 207 patients (mean age 70.47 ± 7.04) with appropriate indication for colonoscopy according to the American Society for Gastrointestinal Endoscopy, 43 (20.77%) patients had some colonoscopy complications: 1 (0.48%) with the sedation (apnea), 4 (1.93%) with the procedure (abdominal pain and bacteremia) and 38 (18.35%) with the bowel preparation (acute renal failure, hypotension). Individuals ≥80 years had an RR = 3.4 (1.2-10.1),P = 0.025, and those with a Charlson index 3 had an RR = 5.2 (1.6-16.8), P = 0.006, for complications. The cumulative illness rating scale for geriatrics was not associated with complications (P = 0.45).ConclusionThere was a significant risk of complications in ≥80 years and in the group with a Charlson index 3. The cumulative illness rating scale for geriatrics was not a good predictor of risk in this sample.


ContextoA idade tem sido considerada um fator de risco independente para complicações colonoscópicas, especialmente na presença de multimorbidade.ObjetivosO objetivo primário foi verificar a correlação entre idade, multimorbidade e complicações colonoscópicas em idosos.MétodosCoorte retrospectiva de pacientes com 60 anos ou mais submetidos a colonoscopia. Foram coletados idade, multimorbidade (de acordo com os índices cumulative illness scale for geriatrics e Charlson) e complicações relacionadas ao preparo e procedimento (sedação e exame).ResultadoDos 207 pacientes (idade média 70.47 ± 7.04) com indicação apropriada para colonoscopia segundo a Sociedade Americana de Endoscopia Gastrointestinal, 43 (20.77%) tiveram alguma complicação: 1 (0.48%) com complicação pela sedação (apneia), 4 (1.93%) relacionada ao procedimento (dor abdominal e bacteremia) e 38 (18.35%) pelo preparo (insuficiência renal aguda, hipotensão). Pacientes ≥80 anos tiveram RR = 3.4 (1.2-10.1), P= 0.025, para complicações e aqueles com índice de Charlson 3, um RR = 5.2 (1.6-16.8), P= 0.006. Cumulative illness rating scale for geriatrics, não mostrou associação com complicações (P = 0.45).ConclusãoHouve risco significativo de complicação em muito idosos (≥80 years) e no grupo com índice de Charlson 3. Cumulative illness rating scale for geriatrics não se mostrou um bom preditor de risco nesta amostra.

2.
Arq. gastroenterol ; 50(1): 23-30, Jan-Mar/2013. tab, graf
Article in English | LILACS | ID: lil-671342

ABSTRACT

Context Colonoscopy plays an indubitable role in the setting of clinical practice, however, it is an invasive exam; complex, lengthy, embarrassing, not devoid of risks and discomfort that yields fear and anxiety in the majority of patients. In a new era of rising competition between health institutions, where the quality of health care and client satisfaction are praised, studies regarding tolerance-related colonoscopy issues yield great potential to be explored. In the present study, tolerance is defined as willingness to repeat the exam. Objectives Evaluate information associated to bowel preparation, the exam itself and post-examination period that might interfere with the tolerance to the colonoscopy. Methods Analysis of the tolerance to the colonoscopy at three stages (pre, post, and during) through a checklist: patient's questionnaire and a medical assessment form were used. Results In this present study, 91.2% of 373 patients exhibited positive tolerance to the colonoscopy. Aspects related to a negative level of tolerance were patient gender (12.9% of women versus 3.2% of men would not repeat the exam), age extremes (less than 20 years and greater than 80 years of age), and abdominal pain, both during the bowel preparation and after the procedure. Conclusions Gender, age, patient cooperation and abdominal pain were the decisive components regarding tolerance to the colonoscopy. Notably, in two phases of the exam, the abdominal pain was the most important feature associated to a lessened tolerance. .


Contexto É inquestionável o papel da colonoscopia na prática clínica, entretanto, trata-se de exame invasivo, complexo, demorado, impudico, não isento de riscos e desconforto, que gera receio e ansiedade à maioria dos pacientes. Em uma nova época de elevada competição entre instituições de saúde, na qual se valoriza a qualidade dos serviços prestados e satisfação dos clientes, estudos sobre fatores relacionados a tolerância à colonoscopia oferecem grande potencial a ser explorado. No presente estudo considerou-se tolerância a disposição de repetir o exame. Objetivo Analisar informações relacionados ao preparo, exame e pós exame que interferem na tolerância à colonoscopia. Métodos Análise da tolerância à colonoscopia em três momentos da colonoscopia (pré, pós e durante) através de check list: “formulário do paciente” e “ficha de avaliação médica”. Resultados No presente estudo 91.2% de 373 pacientes apresentaram tolerância positiva à colonoscopia. Os fatores relacionados à tolerância negativa foram o sexo feminino (12.9% mulheres and 3.2% dos homens não repetiriam o exame), extremos de idade (<20 anos e >80 anos) e dor abdominal durante o preparo intestinal e após o procedimento. Conclusões Gênero, idade, cooperação do paciente e dor abdominal foram fatores determinantes da tolerância à colonoscopia. Significativa em duas fases do exame, a dor abdominal foi o fator mais importante relacionado à redução da tolerância. .


Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Colonoscopy , Patient Acceptance of Health Care , Age Factors , Abdominal Pain/etiology , Colonoscopy/adverse effects , Colonoscopy/psychology , Colonoscopy/statistics & numerical data , Prospective Studies , Patient Acceptance of Health Care/psychology , Patient Acceptance of Health Care/statistics & numerical data , Preoperative Care/psychology , Sex Factors , Surveys and Questionnaires
3.
São Paulo; s.n; 2003. 84 p. ilus, tab.
Thesis in Portuguese | LILACS | ID: lil-408868

ABSTRACT

Foram realizadas biópsias seriadas do íleo terminal e cólon em 162 pacientes com diarréia crônica e colonoscopia normal, objetivando avaliar se a ocorrência de alterações histológicas contribuiria para a elucidação diagnóstica, bem como se a distribuição anatômica destas lesões ao longo do cólon permitiria o estudo somente das regiões distais, através da retossigmoidoscopia, como procedimento inicial. Foram encontradas alterações histológicas com possível significado diagnóstico em 32 por cento dos pacientes. Em 22 por cento, com importância clínica decisiva para a elucidação diagnóstica. Os 10 por cento restantes, representados por pacientes com lesões limítrofes das colites colagenosa e linfocitária e melanosis coli, apontaram para a necessidade do aprofundamento da investigação e seguimento clínico. A distribuição destes achados mostrou a importância de estudarmos todos os segmentos colônicos e não somente a região retossigmoideana.Multiple biopsies along the terminal ileum and colon were taken in 162 patients with chronic diarrhea and normal colonoscopy, to find out the yield of histologic changes in the diagnostic elucidation and if the anatomic distribution of these lesions along the colon would enable the study of only distal areas by performing retosigmoidoscopy as the initial procedure. Histologic lesions with possible diagnostic yield were found in 32 per cent of these patients. In 22 per cent they had clinical significance and were decisive for the final diagnosis. In the remaining 10 per cent the presence of patients with some features of collagenous and lymphocytic colitis and melonosis coli pointed to the need of more thorough investigation and follow-up. The distribution of these histologic changes showed the importance of studying all colon segments and not only the retosigmoid area...


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Colitis/diagnosis , Colitis/pathology , Colonoscopy/methods , Diarrhea/diagnosis , Diarrhea/pathology
4.
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo ; 55(6): 201-206, Nov.-Dec. 2000. tab
Article in English | LILACS | ID: lil-283233

ABSTRACT

A low frequency of Helicobacter pylori in the gastric mucosa of patients with alkaline gastritis has been reported. At the same time, it can be noted that the growth of bacteria can be inhibited by bile acids. We studied 40 patients with chronic gastritis related to Helicobacter pylori in order to determine the effect of ursodeoxycholic acid on this infection. Diagnoses of the infection and the inflammatory process were obtained by histologic study of gastric biopsies collected during endoscopy. Two groups were studied: group I received ursodeoxycholic acid - 300 mg/day, and group II received the placebo, twice a day, both for 28 days. The colonization by Helicobacter pylori and the intensity of the mononuclear and polymorphonuclear inflammatory infiltrate were determined before (time 1) and after (time 2) treatment. Ursodeoxycholic acid had no effect on the Helicobacter pylori infection. A significant reduction in the intensity of the mononuclear inflammatory infiltrate of the gastric antrum mucosa was observed in patients from group I, when we compared not only times 1 and 2 but also groups I and II. However, this was not the case with the body mucosa. We concluded that ursodeoxycholic acid had no action on the colonization by Helicobacter pylori or on the polymorphonuclear inflammatory infiltrate, but it caused a significant reduction in the intensity of the mononuclear inflammatory infiltrate of the gastric antrum


Subject(s)
Humans , Male , Female , Adult , Gastric Mucosa/microbiology , Gastritis/microbiology , Helicobacter pylori/drug effects , Ursodeoxycholic Acid/pharmacology , Age Distribution , Gastric Mucosa/drug effects , Gastric Mucosa/pathology , Gastritis/drug therapy , Gastritis/pathology , Helicobacter pylori/growth & development , Inflammation , Pyloric Antrum/drug effects , Pyloric Antrum/microbiology , Pyloric Antrum/pathology , Sex Distribution , Ursodeoxycholic Acid/therapeutic use
5.
Rev. med. Hosp. Univ ; 7(1): 33-8, jan.-jun. 1997. ilus, tab
Article in Portuguese | LILACS | ID: lil-240675

ABSTRACT

Os autores fazem a revisào da literatura sobre a infecção da mucosa gástrica pelo "Helicobater pylori" com ênfase sobre sua microbiologia, epidemiologia, relaçào com as doenças do estômago, diagnóstico e tratamento (au)


Subject(s)
Humans , Helicobacter pylori , Helicobacter Infections , Adenocarcinoma/microbiology , Helicobacter pylori/pathogenicity , Lymphoma, B-Cell, Marginal Zone/microbiology , Dyspepsia/microbiology , Gastritis/microbiology , Helicobacter Infections/diagnosis , Helicobacter Infections/drug therapy , Stomach Neoplasms/microbiology , Peptic Ulcer/microbiology
6.
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo ; 44(5): 189-92, set.-out. 1989. tab
Article in Portuguese | LILACS | ID: lil-89047

ABSTRACT

Analisa-se o total de pacientes operados de úlcera péptica no Hospital das Clínicas da Faculdade de Medicina da USP entre 1966 e 1985, para verficar variaçöes com a introduçäo da cimetidine a partir de 1978. foi observada reduçäo na freqüência das cirurgias, que se tornou mais nítida a partir de 1978. Para estudo mais pormenorizado das mesmas variaçöes tomou-se amostra aleatória de 10% das cirurgias entre 1973 e 1985. Neste caso verificou-se reduçäo na feqüência de cirurgias para úlcera péptica estenosante e hemorrágica e diminuiçäo nas úlceras pépticas perfuradas. Näo ocorreu diferença significante em relaçäo ao sexo e a idade dos pacientes, exceto nas úlceras pépticas perfuradas onde ocorreu aumento do número de mulheres


Subject(s)
Humans , Male , Female , Cimetidine/therapeutic use , Peptic Ulcer/surgery , Analysis of Variance , Histamine H2 Antagonists/therapeutic use , Sampling Studies , Peptic Ulcer/complications
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